Measles incidence, nonmeasles infectious disease mortality, and measles-induced immunomodulation.jpg
To mi pripomina (tady to strasny placani nade mnou...tohle vlakno je nejak obzvlast atraktivni pro mistni blazny :think: ) jednu hezkou studii: https://science.sciencemag.org/content/348/6235/694 "Immunosuppression after measles is known to predispose people to opportunistic infections for a period of several weeks to months. Using population-level data, we show that measles has a more prolonged effect on host resistance, extending over 2 to 3 years. We find that nonmeasles infectious disease mortality in high-income countries is tightly coupled to measles incidence at this lag, **in both the pre- and post-vaccine eras**. We conclude that long-term immunologic sequelae of measles drive interannual fluctuations in nonmeasles deaths. This is consistent with recent experimental work that attributes the immunosuppressive effects of measles to depletion of B and T lymphocytes. Our data provide an explanation for the long-term benefits of measles vaccination in preventing all-cause infectious disease. By preventing measles-associated immune memory loss, vaccination protects polymicrobial herd immunity."
- Autor: Lenka_Hal
- Vloženo: 06.10.19
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